I was staking a tall plant last night without gloves and woke this morning to a blisters on my face and a swollen eye. I am pretty sure it was the plant as I started feeling the numbness on my face before going to sleep. I heard about the giant hogweed but it does not resemble it. It is about 5' high now, grown from a bulb or existing root (new home so unsure of the gardens) and has round green buds but no flower yet.
Sounds like a Euphorbia. Hundreds, if not thousands, of species and cultivars, and quite a few in local cultivation. Would need a photo to confirm -- yours won't be this particular species, but you can read a number of horror stories here (most, if not all, will cause the same reaction): Euphorbia myrsinites
Thanks for leading me in the right direction. The plant that caused some nasty blisters and swelling on my skin is the Euphorbia Lathyris (Mole Plant).